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Specifically, for patients with head and neck cancerswho frequently undergo radiation therapy as a part of their treatment regimenthe risk of inadvertent brain exposure to radiation and subsequent ferroptosis-induced brain injury is a significant concern

AaMIXTA1, encoding an R2R3MYB TF, interacts with AaHD8, an HD-ZIP IV TF, forming a regulatory complex that directly promotes AaHD1 expression and positively regulates the initiation of GTs 32,33,34