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In every primate study, kidney effects emerged as the primary side effect

The PS for the adjustment of efficacy constituted the following variables: independent variables such as bevacizumab combination, chemotherapeutic regimen, relapses after radical radiotherapy or surgical resection, ECOG-PS, driver mutation, BMI, chemotherapy line, reduced dosage requirement status, duration of premedication, and comorbidities (respiratory, gastrointestinal, neuropsychiatric, urologic-renal, and dermato-orthopedic), with a C-statistic of 0.823

Including chlorthalidone and hydrochlorothiazide

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Most people start with a loading phase, typically one injection per week for 4 to 6 weeks