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The Gibbon leukemia virus fusion glycoprotein (GALV-GP) increases the efficiency of viral vector entry while inducing cell fusion, significantly boosting tumor cell death in vitro and promoting tumor shrinkage in vivo ( 84, 85)

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This process establishes a vicious cycle: mitochondrial damage leads to inflammasome activation, which in turn exacerbates mitochondrial damage (137, 138)

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