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Together, these clinical findings suggest that glial metabolic dysfunction may contribute to age-related neurodegenerative disorders

Factors such as sunlight, hormonal changes, drugs and skin injuries can cause excessive melanin production

Plants have therefore been a potential source of antioxidants which have received a great deal of attention since increased oxidative stress has been identified as a major causative factor in the development and progression of several life-threatening diseases, including neurodegenerative and cardiovascular diseases and wound infection

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