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Similar content being viewed by others Introduction Neutrophils, the most predominant type of granulocyte, comprise 4070% of all human leukocytes

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however, they fail to effectively promote CD8 T cell infiltration

However, the vast majority require therapeutic intervention.2 Drug treatments for diabetes aim to control blood glucose levels, yet studies have shown tight glycaemic control does not decrease the cardiac complications of T2D.54 Independent of treatment status, T2D patients have increased risk for all-cause and cardiovascular-related mortality, as well as HF-related hospitalisation compared with non-diabetics.55 1

*Correspondence: Daqi Zhang, [email protected] Li, [email protected] These authors have contributed equally to this work This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers