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This higher closing pressure leads to earlier closure of the aortic valve

It may happen when your pupil changes and becomes too big (dilated) too quickly

it showed that risk rises with long-term high Lp(a).[ref] Waist-to-hip ratio as a modifying factor for atherosclerosis: A 2025 study involving ~800 people with Lp(a) over 50 mg/dL showed that those with a larger waist-to-hip ratio (more belly fat) were at a much higher risk of atherosclerosis