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Subsequently, it was found that co-inactivation of DHODH and mitochondrial GPX4 led to mitochondrial lipid peroxidation and that BQR treatment significantly increased the intracellular CoQ10/CoQH2 ratio [103], suggesting that DHODH inhibits mitochondrial lipid peroxidation by reducing CoQ10 to CoQH2 in concert with mitochondrial GPX4

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e2020GB006602 Colina M, Kosten S, Silvera N, Clemente JM, Meerhoff M (2021) Carbon fluxes in subtropical shallow lakes: contrasting regimes differ in CH 4 emissions