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doi: 10.3390/molecules21121694 481 Delgado-RocheLGonzlezKMestaFCouderBTavarezZZavalaRet al

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Sulforaphane improves lipid metabolism by enhancing mitochondrial function and biogenesis in vivo and in vitro

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Whether partial TCA cycle reverse activity due to the large accumulation of fumarate, leading to SDH reversal and fumarate reduction to succinate, as it has been observed in ischaemia [36], or cells treated with mitochondrial inhibitors [37], occurs in Fh -1 deficient cells has not been reported