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The World Anti-Doping Agency (WADA) prohibits AOD-9604 as a non-approved substance and potential performance-enhancing agent in athletics, citing concerns about unfair advantage through lean body mass gains (if efficacious, which remains unproven)

Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes

doi:10.3390/ijerph181910397

The FDA approved semaglutide for type 2 diabetes and weight loss in people with obesity or overweight with at least one weight-related health condition

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