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The change in expression of the GATM gene was strongly associated with statin exposure, and a further analysis of SNPs across the GATM locus revealed rs9806699 as being the most significantly associated differential eQTL (deQTL) after in vitro exposure to simvastatin

When the experimental parameters were tuned just right, the hot systems particles almost immediately found their final configuration, cooling exponentially faster than the warm systema situation that Raz, Vucelja, and colleagues had predicted and named the strong Mpemba effect. They reported the results in a 2020 Nature paper and published similar experiments showing the inverse Mpemba effect in PNAS earlier this year

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