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An independent assessment committee evaluated the endpoints and determined threshold criteria for clinically meaningful responses before the trials unblinding

McGarrity S, Anuforo O, Halldorsson H, Bergmann A, Halldorsson S, Palsson S, Henriksen HH, Johansson PI, Rolfsson O (2018) Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification

Below, we highlight representative microbiota-dependent metabolites that modulate ferroptosis-relevant nodes (iron handling, lipid peroxidation, antioxidant systems) and discuss their translational potential

A patient with glaucoma is also likely to have a visual field test to measure losses in peripheral vision and a visual acuity test to check for visual sharpness (acuity)

Cell death in tumor cells was quantified by multiplex immunofluorescence (mIF) using cleaved Poly (ADP-ribose) polymerase (cPARP) with pan-cytokeratin (PanCK) for tumor mask visualization, Ki67 for context, and DAPI for nuclei