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All patients were males, with a mean age of 52.8 years (DCM patients), 53.2 years (ICM patients), 52.6 years (HCM patients), and 51.6 years (controls)

doi: 10.3389/fpls.2025.1718992 Received 05 October 2025 Accepted 27 October 2025 Published 13 November 2025 Volume 16 - 2025 Edited by Qunfeng Zhang, Chinese Academy of Agricultural Sciences (CAAS), China Reviewed by Yunqiu Yang, Anhui Agricultural University, China Yuanzhi Shi, Chinese Academy of Agricultural Sciences, China Xiangxiang Huang, Fujian Agriculture and Forestry University, China Updates Copyright 2025 An, Mao, Huang, Leng and Chen

For instance, the efficacy of combination relies on using strategies that normalize tumor vasculature and avoids detrimental vascular pruning as described above (144), most anti-angiogenic strategies are complicated by toxic sequelae due to their effects on normal tissues