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Hynes NE Journal article: MOLECULAR PSYCHIATRY

2014 Oct;42(10):2410-8

177 HoffmannKFCheeverAWWynnTA

In mouse aortic endothelial cells MGO administration in form of a pre-treatment impaired insulin-dependent NO production in endothelial cells

MOTS-c has been studied in preclinical research models for its interactions with AMPK (AMP-activated protein kinase) signaling pathways, glucose metabolism regulation, and insulin sensitivity mechanisms, making it a research tool of particular interest to investigators studying mitochondrial biology, metabolic signaling, and cellular energetics