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Furthermore, chronic pulmonary diseases, such as COPD, are often associated with a significant oxidative/antioxidant imbalance [476]

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Future works searching for genetic and post-translational modifications affecting FLNA expression and function, as well as for a possible involvement of other cytoskeleton proteins, might help to clarify the complex mechanisms involved in pituitary tumors pharmacological resistance

174,175 Oxidative stress, proteasome dysfunction, and protein aggregation, changes that frequently occur during aging, have been implicated in the pathogenesis of PD