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Etiologies and predictors of diagnosis in nonresponsive celiac disease

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Previous studies have focused primarily on signaling pathways involved in lipid regulation, such as sirtuin 1 (SIRT1) and AMP-activated protein kinase (AMPK), whereas the specific contributions of growth arrest and DNA damage-inducible 45 (GADD45) in this context remain poorly characterized 6,7

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However, prolonged gastric retention also means delayed arrival at the intrinsic factor binding sites and the ileal absorption receptors