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Description

On one hand, gut-to-lung axis: Circulating gut-derived metabolites (e.g., tryptophan catabolites) directly regulate pulmonary epithelial immunity

The crosstalk between hepcidin-SLC40A1 mediated system iron metabolism and IRP-IRE regulated cellular iron homeostasis is that the IRP-IRE system senses cellular iron starvation and limits iron losses, whereas hepcidin-FPN protects the organism against systemic iron overload