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Also, the phosphopantetheinyl moiety of coenzyme A is required for the biological activity of several proteins, including the acyl-carrier protein involved in fatty acid synthesis

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However, miR-26 also suppresses cholesterol efflux to promote foam cell formation by binding and suppressing ABCA1 and ARL4C in vitro, as observed in RAW264.7 cells, THP-1 cells, and HepG2 cells [23, 59,60,61], suggesting that the formation of foam cells induced by miR-26 may weaken its ability to reduce atherosclerosis

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