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Full healing cycles typically require eight to twelve weeks for optimal collagen remodeling and tissue repair

Tsai C-W, Tsai R-T, Liu S-P, Chen C-S, Tsai M-C, Chien S-H et al (2017) Neuroprotective effects of betulin in pharmacological and transgenic Caenorhabditis elegans models of Parkinsons disease

Although genetics is by far the most important factor, environmental influences, like infections during pregnancy and exposure to pollution, may also play a role