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(2003) found that epithalon may extend lifespan in cell populations and whole organisms via its telomerase activity when introduced to telomerase-negative human fetal fibroblast cultures

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Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis

Two severe adverse events were reported: viral meningitis (in cagrilintide 1.2 mg + semaglutide 2.4 mg) and an increase in serum creatinine (in placebo + semaglutide 2.4 mg), but both events were deemed unrelated to study treatment by the study investigator