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10.1016/j.bbamcr.2008.11.009 Biochim

1.2 Targeting autophagy for cancer therapy Autophagy, a critical mechanism for maintaining cellular balance by removing damaged organelles and protein aggregates, can also facilitate cell death (Liu et al., 2023)

Papi et al., 2023)

Since microtubules play an important role in maintaining cell morphology, establishing cell polarity, and intracellular information transmission, hyperphosphorylated Tau protein could result in the loss of affinity with microtubules and lead to microtubules unstable and disintegrated, which in turn affects the transport and morphological structure of nerve cells, leading to the death of nerve cells [38, 39]

Abundance of noncircular intrahepatic hepatitis B virus DNA may reflect frequent integration into human DNA in chronically infected patients