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High GLS expression in colorectal cancer has been demonstrated to result in reduced T-cell infiltration and toxicity, which is a significant factor contributing to the poor prognosis observed in patients with this condition

As shown in Figure 4, the uptake velocity of the [ 14 C]-labeled 3BP was very similar for all three Prototheca species

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For drugs with intracellular targets, it is important that after reaching the brain ECF, the drug crosses the cellular membrane of the brain parenchymal cells via a transporter expressed in the target cells