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Since modifications in histone and DNA are important for proper repair of DNA DSBs (30), changes in nutrient and substrate levels that disrupt these modifications are bound to affect DNA-repair pathways

Figure 6)

10.1002/syn.890200210 Synapse 103 LuM.HuL

Skin Pharmacol Physiol 31:332336

Skin quality changes (thickness, elasticity, hydration) are sometimes discussed during this timeframe in clinical contexts, though effects when they occur are typically subtle