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Splenectomy is a more invasive option that is generally reserved for severe or treatment-resistant thrombocytopenia (Wang 2012)

Barton, the discussant, took a cautionary view, saying that there are some things to consider before going out and telling patients to consider acetyl-carnitine for their peripheral neuropathy. It was unclear from the results reported whether the two treatment groups were well balanced and what criteria were used to define improvement for the secondary outcomes, she noted

Its generally safe for many adults when used as directed, but pregnant/breastfeeding women and people with medical conditions should consult a doctor first