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In general, by either excess or impairment, NO appears to cause or contribute to a variety of disturbances, in particular, hypertension, angina, impotence, circulatory shock, septic shock, stroke, inflammation, respiratory distress syndromes, pulmonary hypertension, adhesion and aggregation of platelets and leukocytes, diabetes, hypotension, and Parkinson's disease

[13] 4 Apply a cold washcloth over areas that swell up or get inflamed

This raises important questions about how long treatment should continue

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On the other hand, in patients without a history of gastrectomy, the severity and duration of diseases and/or the dose and duration of medication intake could have affected the clinical and laboratory results