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The FSP1-CoQ10-NAD(P)H pathway is a parallel anti-ferroptosis system independent of the cystine-GSH-GPX4 system that inhibits lipid peroxidation and anti-ferroptosis effects, FSP1 has a dual regulatory role: inducing apoptosis and preventing ferroptosis (Wu et al., 2002

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showed in senescent cells widespread mitochondrial outer membrane permeabilization in part of mitochondria enhanced mtDNA leakage to the cytoplasm and subsequent activation of the cGAS-STING pathway

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When you swallow a traditional capsule or tablet, it must pass through the harsh, acidic environment of the stomach