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If concomitant ibuprofen use cannot be avoided, monitor patients more frequently for Pemetrexed Injection adverse reactions, including myelosuppression, renal, and gastrointestinal toxicity [see Dosage and Administration (2.5), Drug Interactions (7), and Clinical Pharmacology (12.3)]

It helps maintain cell integrity and function

Carpal tunnel syndrome Tingling or numbness in the hands due to nerve compression

One-half cup of calcium proprionatek (approximately 40 gms) mixed with water and given by oral calf feeder twice a day or tube may be helpful providing both calcium and proprionate

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