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A., Gdula, M

365 Moreover, activated P-selectin on the surface of platelets in patients with SLE binds to P-selectin glycoprotein ligand-1 modified with CD15s on Tregs, leading to the upregulation of spleen tyrosine kinase-dependent calcium signaling and the inhibition of the TGF- pathway, thereby impairing Treg function

Measurement of iron concentration Iron concentration in FBS or whole-cell lysates was measured using an iron assay kit LS (Ferrozine Method) (FE31ME, Metallogenics) according to the manufacturers instructions