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[4] Studies evaluating the effect of peptide exposure in cell cultures have noted that Epithalon appears to directly interact with promoter regions of certain genes such as Tram1, IL-2, CD5, and MMP2 and may also enhance their expression

Nonmigrated cells were removed with cotton swabs, and migrated cells were fixed with ice-cold methanol and stained with 4,6-diamidino-2-phenylindole (DAPI)