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Transcription factors YAP/TAZ, which reside downstream of VEGF/VEGFR-2, are upregulated on stiffer matrices and in disturbed flow, and in vivo inhibition of YAP/TAZ caused decreased atherosclerosis and EC inflammation (83, 84)

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Importantly, several patients demonstrated significant durations of disease stability following treatment, suggesting DEXs ability to activate immune responses against tumors

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Early diagnosis of diabetic neuropathy is possible if regular screening for this complication is conducted using modern diagnostic methods