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Cancer progression is intricately regulated by both tumor cells and immune cells

Generation of the metabolic models of Fh1 / and Fh1 fl/fl cells / fl/fl To investigate the metabolic changes that occur due to FH-inactivation metabolic models of Fh1 / and Fh1 fl/fl , cell lines were constructed based on their transcriptomics and uptake-secretion metabolomics

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

NF-B inhibition is related to a reduction in proinflammatory cytokine biosynthesis, a decrease in adhering molecule expression, downregulation of the gene encoding cyclooxygenase-2, and the induction of nitric oxide (NO) synthetase [68]