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Starvation therapy is a strategy to treat cancer by depriving tumours deprived of key nutrients [188]

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doi: 10.1016/j.ijid.2018.02.021 152 BaiXOberley-DeeganREBaiAOvrutskyARKinneyWHWeaverMet al

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When iron metabolism is disordered or ATG expression is abnormal, iron autophagy mediated by NCOA4 can induce ferroptosis by degrading ferritin and inducing iron overload ( Hypoxia can also affect iron metabolism

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