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Sattar N, Gaw A, Scherbakova O, Ford I, OReilly DSJ, Haffner SM, Isles C, Macfarlane PW, Packard CJ, Cobbe SM, Shepherd J

Brain Res (2018) 1698:20412

Inhibitors of transporter proteins Many studies have reported that cisplatin can enter cochlear hair cells via various cation transport proteins and MET machinery formed by transmembrane channel-like 1 and 2 (TMC1/2), LHFPL tetraspan subfamily member 5 protein (LHFPL5), transmembrane inner ear protein (TMIE), calcium and integrin-binding family member 2 (CIB2), and tip link proteins (Protocadherin-15 and Cadherin-23) ( A report suggests that the inhibition of MET by quinine or ethylene glycol tetraacetic acid (EGTA) can prevent cisplatin-induced hair cell death (Thomas et al., 2013)

Other reviews uncovered similar limitations: For musculoskeletal injuries, the studies in people are too sparse and low quality to pin down whether the peptide works or what risks it poses

Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell and Tissue Research