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Description

Glutamine-derived -ketoglutarate (-KG) is an essential intermediate in the TCA cycle

Yeast carboxypeptidase Y requires glycosylation for efficient intracellular transport, but not for vacuolar sorting, in vivo stability, or activity

Verma T, Bhardwaj S, Singh J, Kapoor D, Prasad R

To better simulate the clinical situation, a xenograft mouse model derived from PDCs with high and low expression of VRK2 was employed for further study