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A 2025 systematic review by Vasireddi and colleagues in HSS Journal screened 544 published papers and identified 36 meeting inclusion criteria 35 preclinical studies and only one human study: an uncontrolled, unblinded, retrospective case series of 12 patients receiving intra-articular BPC-157 for chronic knee pain, in which 7 of 12 (58%) reported self-described relief lasting more than 6 months, with no dose, effect size, or systematically collected adverse events published

Fat loss can be masked by water retention (menstrual cycle, high sodium intake, inadequate hydration) or lean mass gains from resistance training

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Okhuysen PC, Dupont HL (2010) Enteroaggregative Escherichia coli (EAEC): a cause of acute and persistent diarrhea of worldwide importance

Vitamin C and some supplements may interfere with certain laboratory tests depending on timing and assay method