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Hepatoprotective effect of citral on acetaminophen-induced liver toxicity in mice

The results of this work give insights into the influence of GST-mediated biotransformation on neonicotinoid toxicity and indicate that different molecular mechanisms mediate the toxicity of imidacloprid and thiacloprid in an important soil ecotoxicological model species

10.1021/acsnano.1c04206 ACS Nano

Finally, expanding the innovation pipeline through prodrug development, synergistic combination therapies, and patentable formulation strategies will help overcome current pharmacokinetic challenges and accelerate translation

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