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Oral B12 requires a protein called intrinsic factor in the stomach to be absorbed properly

Mahdi, J

Komoly, 2005

Fe(III)-Shikonin supramolecular nanomedicine for combined therapy of tumor via ferroptosis and necroptosis

Research published in Toxicology and Applied Pharmacology found that copper supplementation above 10mg daily (roughly 5 the RDA) can disrupt zinc homeostasis and trigger oxidative stress in hepatic tissue