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Feature · Product Review
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Description

Using ClinVar, we identified variants that were reported to be pathogenic or likely pathogenic according to ACMG guidelines from the seven aforementioned candidate genes

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Abnormalities in intracellular iron metabolism result in excess iron undergoing a Fenton reaction with hydrogen peroxide (a result of mitochondrial superoxide dismutase reacting on mitochondrial superoxide radicals)

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Therefore, Ursolic acid fails in this category

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doi:10.1016/j.neuropharm.2020.108026 Chen Z, Tian R, She Z, Cai J, Li H

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