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A number of desaturation, isomerization, and cyclization processes are catalyzed by important enzymes such as phytoene desaturase (PDS), -carotene desaturase (ZDS), carotenoid isomerase (CRTISO), and lycopene - and -cyclases (LCYB, LCYE) as shown in Figure 2 ( RIN , NOR , and HYR ), environmental conditions (light, temperature), and hormonal signals (ethylene, abscisic acid)

These outcomes showed that EGb not only augments the antidepressant effects but also facilitates improvements in cognitive functioning and may contribute to the restoration of neurological function in older adult patients (68) (Table 2)

Eur J Immunol (2012) 42(12):320211

Clin J Am Soc Nephrol 9, 14101417 (2014)

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