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Blood draw and plasma EV isolation Blood was collected after an overnight fast at four different timepoints throughout the study: (1) before first exercise training session, (2) immediately after first exercise training session, (3) before final exercise training session, and (4) immediately after final exercise training session

Trp Microbial activity transforms tryptophan (Trp) into various indole derivatives, including tryptamine, indole- 3-acetic acid (IAA), indole- 3-propionic acid (IPA), and indole- 3-carboxaldehyde (IAld)

Liver monoamine oxidase activity was comparable among the three groups ( P = 0103) (Fig

Universal Service Data Object (USDO) USDO services are intended for configuration and diagnostic tasks in CANopen FD systems

the Springboard scheme is funded by Wellcome, the Department of Business, Energy, and Industrial Strategy UK, the British Heart Foundation, and Diabetes UK) and the British Heart Foundation (grant number FS/PhD/22/2932, non-clinical PhD studentship QWH)