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Associated extracted ion chromatograms (mass tolerance window=0.05 Da) are then peak-detected and noise-reduced in both the LC and MS domains such that only true metabolite related features are processed by the software

pp 137151 Pettegrew JW, Nichols JS, Minshew NJ, Rush AJ, Stewart RM

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In one embodiment, the invention provides the use of a compound of formula (I), its stereoisomers and/or its cosmetically or pharmaceutically acceptable salts, for maintaining and/or improving the physical barrier function of the skin and the immunological barrier function of the skin