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When in doubt, compounded medication past its BUD should be treated with more caution than brand-name medication slightly past its expiration date

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The increase in sebum secretion from related sebaceous glands leads to abnormal keratinization of the follicular sebaceous glands, microbial proliferation, inflammation induction as well as initiation of potential immune mechanisms and inflammatory cascade reactions resulting in skin lesion formation (65)

These effects may support orderly collagen deposition and structural realignment during the repair of tendons, ligaments, and muscle tissue, contributing to improved biomechanical recovery