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Figure 11 3.14 The impact of C75 on the lipid metabolism in vivo Finally, immunohistochemical analysis showed that, except for Acsl1 ( Figures 11K, Q ), the expression of lipid metabolism-related genes Fasn ( Figures 11G, M ), Scd1 ( Figures 11H, N ), Dgat2 ( Figures 11I, O ), Acaca ( Figures 11J, P ), and PPAR- ( Figures 11L, R ) were significantly decreased in the SHR+C75 group compared to the SHR+Vehicle group

Given the gene's role in macronutrient metabolism, the PPAR signaling pathway has become a focal point in obesity research, particularly in elucidating the interactions between environmental exposure and gene expression (118)