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Most in vivo studies remain short-term and small-scale, offering limited insight into the chronic oxidative and inflammatory complexity of human wounds

Second, clinical translation should involve establishing multicenter biobanks for preterm infants to validate associations between ferroptosis biomarkers (such as cerebrospinal fluid ACSL4 levels and MRI-detected white-matter iron deposition) and motor development scores (GMFM and Bayley scales)

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