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IL-1R deficient mice are almost completely resistant to AILI [179], and the use of recombinant human IL-1R antagonists also has a protective effect on AILI [55]

References Thermo Scientic

10.1007/s11010-014-2222-0 Mol

Dentener MA, Vernooy JHJ, Hendriks S, Wouters EFM

Similarly, DNA methyltransferase (DNMT) inhibitors alleviate depressive-like behaviors in ethanol-exposed rodents by demethylating BDNF promoters, underscoring the therapeutic potential of epigenetic editing (Shivakumar et al