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Short-chain free-fatty acid G protein-coupled receptors in Colon cancer

Basic reverse-phase fractionation Basic reverse-phase fractionation (bRP) was carried out on an HPLC equipped with an Agilent Zorbax 300 2.1 mm 150 mm column packed with 5 m C18 beads

Notably, the activation of mTOR or S6K1 can lead to the phosphorylation of the insulin receptor substrate-1 (IRS-1) (4345), thereby inhibiting insulin signaling pathways (46)