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It is known that many metabolic processes of the malaria parasite are dependent on iron, such as DNA synthesis, carbohydrate metabolism, proteolysis of host hemoglobin, mitochondrial function and electron transport

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The major sources of free radicals include: Ordinary body functions, such as breathing and digestion Exposure to radiation Exposure to other environmental pollutants Consumption of cigarettes, tobacco, drugs and alcohol Certain medications or high use of antibiotics, which leads to antibiotic resistance A poor diet that includes foods like unhealthy fats, too much sugar, pesticides, herbicides or synthetic additives

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Ramirez-Exposito M.J., Carrera-Gonzalez M.P., Mayas M.D., Martinez-Martos J.M