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We amplified a fragment of (105 bp) from exosomal XM_002400035 sequence that contained Bam HI and Xho I restriction enzyme sites and cloned into expression vector pGEX-6P-2 with glutathione S-transferase (GST) tag (Bioexpress, Kaysville, UT, USA)

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This section discusses MS pathogenesis with emphasis on neuroinflammation and BBB disruption, the roles of dysfunctional innate immune cells, adaptive T and B cell dysregulation, and the resultant pathological outcomes