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Identification of antidiabetic effect of iridoid glycosides and low molecular weight polyphenol fractions of Corni Fructus , a constituent of Hachimi-jio-Gan, in streptozotocin-induced diabetic rats

J Physiol Biochem 68(1):7790 Babu GN, Kumar A, Singh RL (2011) Chronic pretreatment with acetyl-L-carnitine and DL--lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function

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While epidemiological evidence indicates that this motor system disease is associated with poisoning from cyanogenic glucosides found in improperly processed cassava, not all individuals who rely on a cyanogenic diet are affected during outbreaks of konzo, suggesting additional and yet unknown factors required for onset of disease 4,5