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NAC became the standard treatment for acetaminophen poisoning because it replenishes hepatic glutathione depleted by the toxic metabolite NAPQI

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Prophylactic efficacy of quercetin in ameliorating the hypoxia induced vascular leakage in lungs of rats

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In addition, this reaction leads to a disulfide, which, if occurring on a protein could result in S-glutathiolation of the protein thiol