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Another significant concern is that excessive modulation of the Th17/Treg balance carries potential risks, as it may damage the hosts immune defense against pathogens or destroy self-tolerance

However, prolonged or excessive shedding (lasting more than 4-6 weeks or resulting in visible thinning) suggests problems rather than transition

Alpha lipoic acid for symptomatic peripheral neuropathy in patients with diabetes: a meta-analysis of randomized controlled trials